Mild cognitive impairment - beyond controversies, towards a consensus: report of the international working group on Mild Cognitive impairment
Identifieur interne : 00AB94 ( Main/Exploration ); précédent : 00AB93; suivant : 00AB95Mild cognitive impairment - beyond controversies, towards a consensus: report of the international working group on Mild Cognitive impairment
Auteurs : B. Winblad [Suède] ; K. Palmer [Suède] ; M. Kivipelto [Suède] ; V. Jelic [Suède] ; L. Fratiglioni [Suède] ; L.-O. Wahlund [Suède] ; A. Nordberg [Suède] ; L. B Ckman [Suède] ; M. Albert [États-Unis] ; O. Almkvist [Suède] ; H. Arai [Japon] ; H. Basun [Suède] ; K. Blennow [Suède] ; M. De Leon [États-Unis] ; C. Decarli [États-Unis] ; T. Erkinjuntti [Finlande] ; E. Giacobini [Suisse] ; C. Graff [Suède] ; J. Hardy [États-Unis] ; C. Jack [États-Unis] ; A. Jorm [Australie] ; K. Ritchie [France] ; C. Van Duijn [Pays-Bas] ; P. Visser [Pays-Bas] ; R. C. Petersen [États-Unis]Source :
- Journal of internal medicine [ 0954-6820 ] ; 2004.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Médecine.
English descriptors
- KwdEn :
Abstract
The First Key Symposium was held in Stockholm. Sweden, 2-5 September 2003. The aim of the symposium was to integrate clinical and epidemiological perspectives on the topic of Mild Cognitive Impairment (MCI). A multidisciplinary. international group of experts discussed the current status and future directions of MCI, with regard to clinical presentation, cognitive and functional assessment, and the role of neuroimaging, biomarkers and genetics. Agreement on new perspectives, as well as recommendations for management and future research were discussed by the international working group. The specific recommendations for the general MCI criteria include the following: (i) the person is neither normal nor demented; (ii) there is evidence of cognitive deterioration shown by either objectively measured decline over time and/or subjective report of decline by self and/or informant in conjunction with objective cognitive deficits; and (iii) activities of daily living are preserved and complex instrumental functions are either intact or minimally impaired.
Affiliations:
- Australie, Finlande, France, Japon, Pays-Bas, Suisse, Suède, États-Unis
- East Middle Sweden, Hollande-Méridionale, Languedoc-Roussillon, Occitanie (région administrative), Svealand
- Montpellier, Rotterdam, Stockholm, Uppsala
- Université d'Uppsala
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Le document en format XML
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Fratiglioni</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Aging Research Center, Division of Geriatric Epidemiology, Neurotec Department, Karolinska Institutet</s1><s2>Stockholm</s2><s3>SWE</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Wahlund, L O" sort="Wahlund, L O" uniqKey="Wahlund L" first="L.-O." last="Wahlund">L.-O. Wahlund</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Division of Geriatric Medicine, Neurotec Department, Karolinska Institutet</s1><s2>Stockholm</s2><s3>SWE</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Nordberg, A" sort="Nordberg, A" uniqKey="Nordberg A" first="A." last="Nordberg">A. Nordberg</name><affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Division of Molecular Neuropharmacology, Neurotec Department, Karolinska Institutet</s1><s2>Stockholm</s2><s3>SWE</s3><sZ>7 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="B Ckman, L" sort="B Ckman, L" uniqKey="B Ckman L" first="L." last="B Ckman">L. B Ckman</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Aging Research Center, Division of Geriatric Epidemiology, Neurotec Department, Karolinska Institutet</s1><s2>Stockholm</s2><s3>SWE</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Albert, M" sort="Albert, M" uniqKey="Albert M" first="M." last="Albert">M. Albert</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Department of Neurology, John Hopkins University School of Medicine</s1><s2>Baltimore, MD</s2><s3>USA</s3><sZ>9 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Baltimore, MD</wicri:noRegion></affiliation></author><author><name sortKey="Almkvist, O" sort="Almkvist, O" uniqKey="Almkvist O" first="O." last="Almkvist">O. Almkvist</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Division of Geriatric Medicine, Neurotec Department, Karolinska Institutet</s1><s2>Stockholm</s2><s3>SWE</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Arai, H" sort="Arai, H" uniqKey="Arai H" first="H." last="Arai">H. Arai</name><affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Department of Geriatric and Complementary Medicine, Tohoku University Graduate School of Medicine Sendai</s1><s2>Miyagi</s2><s3>JPN</s3><sZ>11 aut.</sZ></inist:fA14><country>Japon</country><wicri:noRegion>Miyagi</wicri:noRegion></affiliation></author><author><name sortKey="Basun, H" sort="Basun, H" uniqKey="Basun H" first="H." last="Basun">H. Basun</name><affiliation wicri:level="4"><inist:fA14 i1="06"><s1>Department of Public Health/Geriatrics, Uppsala University</s1><s3>SWE</s3><sZ>12 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName><orgName type="university">Université d'Uppsala</orgName></affiliation></author><author><name sortKey="Blennow, K" sort="Blennow, K" uniqKey="Blennow K" first="K." last="Blennow">K. Blennow</name><affiliation wicri:level="1"><inist:fA14 i1="07"><s1>Department of Clinical Neuroscience, Sahlgrenska Academy, Gothenburg University</s1><s3>SWE</s3><sZ>13 aut.</sZ></inist:fA14><country>Suède</country><wicri:noRegion>Department of Clinical Neuroscience, Sahlgrenska Academy, Gothenburg University</wicri:noRegion></affiliation></author><author><name sortKey="De Leon, M" sort="De Leon, M" uniqKey="De Leon M" first="M." last="De Leon">M. De Leon</name><affiliation wicri:level="1"><inist:fA14 i1="08"><s1>Center for Brain Heatlth, New York University School of Medicine</s1><s2>New York, NY</s2><s3>USA</s3><sZ>14 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>New York, NY</wicri:noRegion></affiliation></author><author><name sortKey="Decarli, C" sort="Decarli, C" uniqKey="Decarli C" first="C." last="Decarli">C. Decarli</name><affiliation wicri:level="1"><inist:fA14 i1="09"><s1>Department of Neurology, Alzheimer's Disease Center, University of California at Davis</s1><s2>Sacramento, CA</s2><s3>USA</s3><sZ>15 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Sacramento, CA</wicri:noRegion></affiliation></author><author><name sortKey="Erkinjuntti, T" sort="Erkinjuntti, T" uniqKey="Erkinjuntti T" first="T." last="Erkinjuntti">T. Erkinjuntti</name><affiliation wicri:level="1"><inist:fA14 i1="10"><s1>Department of Clinical Neurosciences, Helsinki University Hospital</s1><s2>Helsinki</s2><s3>FIN</s3><sZ>16 aut.</sZ></inist:fA14><country>Finlande</country><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Giacobini, E" sort="Giacobini, E" uniqKey="Giacobini E" first="E." last="Giacobini">E. Giacobini</name><affiliation wicri:level="1"><inist:fA14 i1="11"><s1>Department of Geriatrics, University of Geneva Medical School</s1><s3>CHE</s3><sZ>17 aut.</sZ></inist:fA14><country>Suisse</country><wicri:noRegion>Department of Geriatrics, University of Geneva Medical School</wicri:noRegion></affiliation></author><author><name sortKey="Graff, C" sort="Graff, C" uniqKey="Graff C" first="C." last="Graff">C. Graff</name><affiliation wicri:level="3"><inist:fA14 i1="12"><s1>Division of Experimental Geriatrics, Neurotee Department, Karolinska Institutet</s1><s2>Stockholm</s2><s3>SWE</s3><sZ>18 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Hardy, J" sort="Hardy, J" uniqKey="Hardy J" first="J." last="Hardy">J. Hardy</name><affiliation wicri:level="1"><inist:fA14 i1="13"><s1>Laboratory of Neurogenetics, National Institute on Aging/National Institute of Health</s1><s2>Bethesda, MD</s2><s3>USA</s3><sZ>19 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Bethesda, MD</wicri:noRegion></affiliation></author><author><name sortKey="Jack, C" sort="Jack, C" uniqKey="Jack C" first="C." last="Jack">C. Jack</name><affiliation wicri:level="1"><inist:fA14 i1="14"><s1>Department of Diagnostic Radiology and MR Research Laboratory, Mayo Clinic</s1><s2>Rochester, MN</s2><s3>USA</s3><sZ>20 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Rochester, MN</wicri:noRegion></affiliation></author><author><name sortKey="Jorm, A" sort="Jorm, A" uniqKey="Jorm A" first="A." last="Jorm">A. Jorm</name><affiliation wicri:level="1"><inist:fA14 i1="15"><s1>Centre for Mental Health Research, Australian National University</s1><s2>Canberra</s2><s3>AUS</s3><sZ>21 aut.</sZ></inist:fA14><country>Australie</country><wicri:noRegion>Canberra</wicri:noRegion></affiliation></author><author><name sortKey="Ritchie, K" sort="Ritchie, K" uniqKey="Ritchie K" first="K." last="Ritchie">K. Ritchie</name><affiliation wicri:level="3"><inist:fA14 i1="16"><s1>Department of Nervous System IPathologies, French National Institute of Medical Research (INSERM)</s1><s2>Montpellier</s2><s3>FRA</s3><sZ>22 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Van Duijn, C" sort="Van Duijn, C" uniqKey="Van Duijn C" first="C." last="Van Duijn">C. Van Duijn</name><affiliation wicri:level="3"><inist:fA14 i1="17"><s1>Departments of Epidemiology and Biostatistics and Clinical Genetics, Erasmus Medical Center</s1><s2>Rotterdam</s2><s3>NLD</s3><sZ>23 aut.</sZ></inist:fA14><country>Pays-Bas</country><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Visser, P" sort="Visser, P" uniqKey="Visser P" first="P." last="Visser">P. Visser</name><affiliation wicri:level="1"><inist:fA14 i1="18"><s1>Department of Psychiatry and Neuropsychology, University of Mastricht</s1><s3>NLD</s3><sZ>24 aut.</sZ></inist:fA14><country>Pays-Bas</country><wicri:noRegion>Department of Psychiatry and Neuropsychology, University of Mastricht</wicri:noRegion></affiliation></author><author><name sortKey="Petersen, R C" sort="Petersen, R C" uniqKey="Petersen R" first="R. C." last="Petersen">R. C. Petersen</name><affiliation wicri:level="1"><inist:fA14 i1="19"><s1>Department of Neurology, Mayo Clinic</s1><s2>Rochester, MN</s2><s3>USA</s3><sZ>25 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Rochester, MN</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">04-0495781</idno><date when="2004">2004</date><idno type="stanalyst">PASCAL 04-0495781 INIST</idno><idno type="RBID">Pascal:04-0495781</idno><idno type="wicri:Area/PascalFrancis/Corpus">004C98</idno><idno type="wicri:Area/PascalFrancis/Curation">001416</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">004A61</idno><idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">004A61</idno><idno type="wicri:doubleKey">0954-6820:2004:Winblad B:mild:cognitive:impairment</idno><idno type="wicri:Area/Main/Merge">00B888</idno><idno type="wicri:Area/Main/Curation">00AB94</idno><idno type="wicri:Area/Main/Exploration">00AB94</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Mild cognitive impairment - beyond controversies, towards a consensus: report of the international working group on Mild Cognitive impairment</title><author><name sortKey="Winblad, B" sort="Winblad, B" uniqKey="Winblad B" first="B." last="Winblad">B. Winblad</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Division of Geriatric Medicine, Neurotec Department, Karolinska Institutet</s1><s2>Stockholm</s2><s3>SWE</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Palmer, K" sort="Palmer, K" uniqKey="Palmer K" first="K." last="Palmer">K. Palmer</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Aging Research Center, Division of Geriatric Epidemiology, Neurotec Department, Karolinska Institutet</s1><s2>Stockholm</s2><s3>SWE</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Kivipelto, M" sort="Kivipelto, M" uniqKey="Kivipelto M" first="M." last="Kivipelto">M. Kivipelto</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Aging Research Center, Division of Geriatric Epidemiology, Neurotec Department, Karolinska Institutet</s1><s2>Stockholm</s2><s3>SWE</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Jelic, V" sort="Jelic, V" uniqKey="Jelic V" first="V." last="Jelic">V. Jelic</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Division of Geriatric Medicine, Neurotec Department, Karolinska Institutet</s1><s2>Stockholm</s2><s3>SWE</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Fratiglioni, L" sort="Fratiglioni, L" uniqKey="Fratiglioni L" first="L." last="Fratiglioni">L. Fratiglioni</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Aging Research Center, Division of Geriatric Epidemiology, Neurotec Department, Karolinska Institutet</s1><s2>Stockholm</s2><s3>SWE</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Wahlund, L O" sort="Wahlund, L O" uniqKey="Wahlund L" first="L.-O." last="Wahlund">L.-O. Wahlund</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Division of Geriatric Medicine, Neurotec Department, Karolinska Institutet</s1><s2>Stockholm</s2><s3>SWE</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Nordberg, A" sort="Nordberg, A" uniqKey="Nordberg A" first="A." last="Nordberg">A. Nordberg</name><affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Division of Molecular Neuropharmacology, Neurotec Department, Karolinska Institutet</s1><s2>Stockholm</s2><s3>SWE</s3><sZ>7 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="B Ckman, L" sort="B Ckman, L" uniqKey="B Ckman L" first="L." last="B Ckman">L. B Ckman</name><affiliation wicri:level="3"><inist:fA14 i1="02"><s1>Aging Research Center, Division of Geriatric Epidemiology, Neurotec Department, Karolinska Institutet</s1><s2>Stockholm</s2><s3>SWE</s3><sZ>2 aut.</sZ><sZ>3 aut.</sZ><sZ>5 aut.</sZ><sZ>8 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Albert, M" sort="Albert, M" uniqKey="Albert M" first="M." last="Albert">M. Albert</name><affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Department of Neurology, John Hopkins University School of Medicine</s1><s2>Baltimore, MD</s2><s3>USA</s3><sZ>9 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Baltimore, MD</wicri:noRegion></affiliation></author><author><name sortKey="Almkvist, O" sort="Almkvist, O" uniqKey="Almkvist O" first="O." last="Almkvist">O. Almkvist</name><affiliation wicri:level="3"><inist:fA14 i1="01"><s1>Division of Geriatric Medicine, Neurotec Department, Karolinska Institutet</s1><s2>Stockholm</s2><s3>SWE</s3><sZ>1 aut.</sZ><sZ>4 aut.</sZ><sZ>6 aut.</sZ><sZ>10 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Arai, H" sort="Arai, H" uniqKey="Arai H" first="H." last="Arai">H. Arai</name><affiliation wicri:level="1"><inist:fA14 i1="05"><s1>Department of Geriatric and Complementary Medicine, Tohoku University Graduate School of Medicine Sendai</s1><s2>Miyagi</s2><s3>JPN</s3><sZ>11 aut.</sZ></inist:fA14><country>Japon</country><wicri:noRegion>Miyagi</wicri:noRegion></affiliation></author><author><name sortKey="Basun, H" sort="Basun, H" uniqKey="Basun H" first="H." last="Basun">H. Basun</name><affiliation wicri:level="4"><inist:fA14 i1="06"><s1>Department of Public Health/Geriatrics, Uppsala University</s1><s3>SWE</s3><sZ>12 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Uppsala</settlement><region nuts="1">Svealand</region><region nuts="1">East Middle Sweden</region></placeName><orgName type="university">Université d'Uppsala</orgName></affiliation></author><author><name sortKey="Blennow, K" sort="Blennow, K" uniqKey="Blennow K" first="K." last="Blennow">K. Blennow</name><affiliation wicri:level="1"><inist:fA14 i1="07"><s1>Department of Clinical Neuroscience, Sahlgrenska Academy, Gothenburg University</s1><s3>SWE</s3><sZ>13 aut.</sZ></inist:fA14><country>Suède</country><wicri:noRegion>Department of Clinical Neuroscience, Sahlgrenska Academy, Gothenburg University</wicri:noRegion></affiliation></author><author><name sortKey="De Leon, M" sort="De Leon, M" uniqKey="De Leon M" first="M." last="De Leon">M. De Leon</name><affiliation wicri:level="1"><inist:fA14 i1="08"><s1>Center for Brain Heatlth, New York University School of Medicine</s1><s2>New York, NY</s2><s3>USA</s3><sZ>14 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>New York, NY</wicri:noRegion></affiliation></author><author><name sortKey="Decarli, C" sort="Decarli, C" uniqKey="Decarli C" first="C." last="Decarli">C. Decarli</name><affiliation wicri:level="1"><inist:fA14 i1="09"><s1>Department of Neurology, Alzheimer's Disease Center, University of California at Davis</s1><s2>Sacramento, CA</s2><s3>USA</s3><sZ>15 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Sacramento, CA</wicri:noRegion></affiliation></author><author><name sortKey="Erkinjuntti, T" sort="Erkinjuntti, T" uniqKey="Erkinjuntti T" first="T." last="Erkinjuntti">T. Erkinjuntti</name><affiliation wicri:level="1"><inist:fA14 i1="10"><s1>Department of Clinical Neurosciences, Helsinki University Hospital</s1><s2>Helsinki</s2><s3>FIN</s3><sZ>16 aut.</sZ></inist:fA14><country>Finlande</country><wicri:noRegion>Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Giacobini, E" sort="Giacobini, E" uniqKey="Giacobini E" first="E." last="Giacobini">E. Giacobini</name><affiliation wicri:level="1"><inist:fA14 i1="11"><s1>Department of Geriatrics, University of Geneva Medical School</s1><s3>CHE</s3><sZ>17 aut.</sZ></inist:fA14><country>Suisse</country><wicri:noRegion>Department of Geriatrics, University of Geneva Medical School</wicri:noRegion></affiliation></author><author><name sortKey="Graff, C" sort="Graff, C" uniqKey="Graff C" first="C." last="Graff">C. Graff</name><affiliation wicri:level="3"><inist:fA14 i1="12"><s1>Division of Experimental Geriatrics, Neurotee Department, Karolinska Institutet</s1><s2>Stockholm</s2><s3>SWE</s3><sZ>18 aut.</sZ></inist:fA14><country>Suède</country><placeName><settlement type="city">Stockholm</settlement><region nuts="2">Svealand</region></placeName></affiliation></author><author><name sortKey="Hardy, J" sort="Hardy, J" uniqKey="Hardy J" first="J." last="Hardy">J. Hardy</name><affiliation wicri:level="1"><inist:fA14 i1="13"><s1>Laboratory of Neurogenetics, National Institute on Aging/National Institute of Health</s1><s2>Bethesda, MD</s2><s3>USA</s3><sZ>19 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Bethesda, MD</wicri:noRegion></affiliation></author><author><name sortKey="Jack, C" sort="Jack, C" uniqKey="Jack C" first="C." last="Jack">C. Jack</name><affiliation wicri:level="1"><inist:fA14 i1="14"><s1>Department of Diagnostic Radiology and MR Research Laboratory, Mayo Clinic</s1><s2>Rochester, MN</s2><s3>USA</s3><sZ>20 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Rochester, MN</wicri:noRegion></affiliation></author><author><name sortKey="Jorm, A" sort="Jorm, A" uniqKey="Jorm A" first="A." last="Jorm">A. Jorm</name><affiliation wicri:level="1"><inist:fA14 i1="15"><s1>Centre for Mental Health Research, Australian National University</s1><s2>Canberra</s2><s3>AUS</s3><sZ>21 aut.</sZ></inist:fA14><country>Australie</country><wicri:noRegion>Canberra</wicri:noRegion></affiliation></author><author><name sortKey="Ritchie, K" sort="Ritchie, K" uniqKey="Ritchie K" first="K." last="Ritchie">K. Ritchie</name><affiliation wicri:level="3"><inist:fA14 i1="16"><s1>Department of Nervous System IPathologies, French National Institute of Medical Research (INSERM)</s1><s2>Montpellier</s2><s3>FRA</s3><sZ>22 aut.</sZ></inist:fA14><country>France</country><placeName><region type="region">Occitanie (région administrative)</region><region type="old region">Languedoc-Roussillon</region><settlement type="city">Montpellier</settlement></placeName></affiliation></author><author><name sortKey="Van Duijn, C" sort="Van Duijn, C" uniqKey="Van Duijn C" first="C." last="Van Duijn">C. Van Duijn</name><affiliation wicri:level="3"><inist:fA14 i1="17"><s1>Departments of Epidemiology and Biostatistics and Clinical Genetics, Erasmus Medical Center</s1><s2>Rotterdam</s2><s3>NLD</s3><sZ>23 aut.</sZ></inist:fA14><country>Pays-Bas</country><placeName><settlement type="city">Rotterdam</settlement><region nuts="2" type="province">Hollande-Méridionale</region></placeName></affiliation></author><author><name sortKey="Visser, P" sort="Visser, P" uniqKey="Visser P" first="P." last="Visser">P. Visser</name><affiliation wicri:level="1"><inist:fA14 i1="18"><s1>Department of Psychiatry and Neuropsychology, University of Mastricht</s1><s3>NLD</s3><sZ>24 aut.</sZ></inist:fA14><country>Pays-Bas</country><wicri:noRegion>Department of Psychiatry and Neuropsychology, University of Mastricht</wicri:noRegion></affiliation></author><author><name sortKey="Petersen, R C" sort="Petersen, R C" uniqKey="Petersen R" first="R. C." last="Petersen">R. C. Petersen</name><affiliation wicri:level="1"><inist:fA14 i1="19"><s1>Department of Neurology, Mayo Clinic</s1><s2>Rochester, MN</s2><s3>USA</s3><sZ>25 aut.</sZ></inist:fA14><country>États-Unis</country><wicri:noRegion>Rochester, MN</wicri:noRegion></affiliation></author></analytic><series><title level="j" type="main">Journal of internal medicine</title><title level="j" type="abbreviated">J. intern. med.</title><idno type="ISSN">0954-6820</idno><imprint><date when="2004">2004</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Journal of internal medicine</title><title level="j" type="abbreviated">J. intern. med.</title><idno type="ISSN">0954-6820</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Alzheimer disease</term><term>Criterion</term><term>Definition</term><term>International</term><term>Medicine</term><term>Report</term><term>mild cognitive impairment</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Déficit cognitif léger</term><term>Compte rendu</term><term>International</term><term>Démence Alzheimer</term><term>Définition</term><term>Critère</term><term>Médecine</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Médecine</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">The First Key Symposium was held in Stockholm. Sweden, 2-5 September 2003. The aim of the symposium was to integrate clinical and epidemiological perspectives on the topic of Mild Cognitive Impairment (MCI). A multidisciplinary. international group of experts discussed the current status and future directions of MCI, with regard to clinical presentation, cognitive and functional assessment, and the role of neuroimaging, biomarkers and genetics. Agreement on new perspectives, as well as recommendations for management and future research were discussed by the international working group. The specific recommendations for the general MCI criteria include the following: (i) the person is neither normal nor demented; (ii) there is evidence of cognitive deterioration shown by either objectively measured decline over time and/or subjective report of decline by self and/or informant in conjunction with objective cognitive deficits; and (iii) activities of daily living are preserved and complex instrumental functions are either intact or minimally impaired.</div></front></TEI><affiliations><list><country><li>Australie</li><li>Finlande</li><li>France</li><li>Japon</li><li>Pays-Bas</li><li>Suisse</li><li>Suède</li><li>États-Unis</li></country><region><li>East Middle Sweden</li><li>Hollande-Méridionale</li><li>Languedoc-Roussillon</li><li>Occitanie (région administrative)</li><li>Svealand</li></region><settlement><li>Montpellier</li><li>Rotterdam</li><li>Stockholm</li><li>Uppsala</li></settlement><orgName><li>Université d'Uppsala</li></orgName></list><tree><country name="Suède"><region name="Svealand"><name sortKey="Winblad, B" sort="Winblad, B" uniqKey="Winblad B" first="B." last="Winblad">B. Winblad</name></region><name sortKey="Almkvist, O" sort="Almkvist, O" uniqKey="Almkvist O" first="O." last="Almkvist">O. Almkvist</name><name sortKey="B Ckman, L" sort="B Ckman, L" uniqKey="B Ckman L" first="L." last="B Ckman">L. B Ckman</name><name sortKey="Basun, H" sort="Basun, H" uniqKey="Basun H" first="H." last="Basun">H. Basun</name><name sortKey="Blennow, K" sort="Blennow, K" uniqKey="Blennow K" first="K." last="Blennow">K. Blennow</name><name sortKey="Fratiglioni, L" sort="Fratiglioni, L" uniqKey="Fratiglioni L" first="L." last="Fratiglioni">L. Fratiglioni</name><name sortKey="Graff, C" sort="Graff, C" uniqKey="Graff C" first="C." last="Graff">C. Graff</name><name sortKey="Jelic, V" sort="Jelic, V" uniqKey="Jelic V" first="V." last="Jelic">V. Jelic</name><name sortKey="Kivipelto, M" sort="Kivipelto, M" uniqKey="Kivipelto M" first="M." last="Kivipelto">M. Kivipelto</name><name sortKey="Nordberg, A" sort="Nordberg, A" uniqKey="Nordberg A" first="A." last="Nordberg">A. Nordberg</name><name sortKey="Palmer, K" sort="Palmer, K" uniqKey="Palmer K" first="K." last="Palmer">K. Palmer</name><name sortKey="Wahlund, L O" sort="Wahlund, L O" uniqKey="Wahlund L" first="L.-O." last="Wahlund">L.-O. Wahlund</name></country><country name="États-Unis"><noRegion><name sortKey="Albert, M" sort="Albert, M" uniqKey="Albert M" first="M." last="Albert">M. Albert</name></noRegion><name sortKey="De Leon, M" sort="De Leon, M" uniqKey="De Leon M" first="M." last="De Leon">M. De Leon</name><name sortKey="Decarli, C" sort="Decarli, C" uniqKey="Decarli C" first="C." last="Decarli">C. Decarli</name><name sortKey="Hardy, J" sort="Hardy, J" uniqKey="Hardy J" first="J." last="Hardy">J. Hardy</name><name sortKey="Jack, C" sort="Jack, C" uniqKey="Jack C" first="C." last="Jack">C. Jack</name><name sortKey="Petersen, R C" sort="Petersen, R C" uniqKey="Petersen R" first="R. C." last="Petersen">R. C. Petersen</name></country><country name="Japon"><noRegion><name sortKey="Arai, H" sort="Arai, H" uniqKey="Arai H" first="H." last="Arai">H. Arai</name></noRegion></country><country name="Finlande"><noRegion><name sortKey="Erkinjuntti, T" sort="Erkinjuntti, T" uniqKey="Erkinjuntti T" first="T." last="Erkinjuntti">T. Erkinjuntti</name></noRegion></country><country name="Suisse"><noRegion><name sortKey="Giacobini, E" sort="Giacobini, E" uniqKey="Giacobini E" first="E." last="Giacobini">E. Giacobini</name></noRegion></country><country name="Australie"><noRegion><name sortKey="Jorm, A" sort="Jorm, A" uniqKey="Jorm A" first="A." last="Jorm">A. Jorm</name></noRegion></country><country name="France"><region name="Occitanie (région administrative)"><name sortKey="Ritchie, K" sort="Ritchie, K" uniqKey="Ritchie K" first="K." last="Ritchie">K. Ritchie</name></region></country><country name="Pays-Bas"><region name="Hollande-Méridionale"><name sortKey="Van Duijn, C" sort="Van Duijn, C" uniqKey="Van Duijn C" first="C." last="Van Duijn">C. Van Duijn</name></region><name sortKey="Visser, P" sort="Visser, P" uniqKey="Visser P" first="P." last="Visser">P. Visser</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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